|Application ||WB, E|
|Other Accession||Q5GH61, Q9QXY7, NP_066569.1|
|Calculated MW||50902 Da|
|Antigen Region||83-111 aa|
|Other Names||Membrane transport protein XK, Kell complex 37 kDa component, Kx antigen, XK-related protein 1, XK, XKR1, XRG1|
|Target/Specificity||This XK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83-111 amino acids from the N-terminal region of human XK.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||XK Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in sodium-dependent transport of neutral amino acids or oligopeptides.|
|Cellular Location||Membrane; Multi-pass membrane protein|
|Tissue Location||High levels in skeletal muscle, heart, brain, and pancreas; low levels in placenta, lung, liver, and kidney|
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Provided below are standard protocols that you may find useful for product applications.
This locus controls the synthesis of the Kell blood group 'precursor substance' (Kx). Mutations in this gene have been associated with McLeod syndrome, an X-linked, recessive disorder characterized by abnormalities in the neuromuscular and hematopoietic systems. The encoded protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins.
Miranda, M., et al. Mov. Disord. 22(9):1358-1361(2007)
Claperon, A., et al. Brain Res. 1147, 12-24 (2007) :
Walker, R.H., et al. Transfusion 47(2):299-305(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Jung, H.H., et al. Transfusion 43(7):928-938(2003)
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