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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   RLN2 Antibody (C-term)   

RLN2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - RLN2 Antibody (C-term) AP19181B
    RLN2 Antibody (C-term) (Cat. #AP19181b) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the RLN2 antibody detected the RLN2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P04090
Other Accession NP_005050.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 21043 Da
Antigen Region 139-165 aa
Additional Information
Gene ID 6019
Other Names Prorelaxin H2, Relaxin B chain, Relaxin A chain, RLN2
Target/Specificity This RLN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 139-165 amino acids from the C-terminal region of human RLN2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRLN2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RLN2
Function Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.
Cellular Location Secreted.
Tissue Location Isoform 1 is expressed in the ovary during pregnancy. Also expressed in placenta, decidua and prostate Isoform 2 is relatively abundant in placenta. It is in much lower abundance in the prostate gland. Not detected in the ovary
Research Areas
Citations (0)

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Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. The active form of the encoded protein consists of an A chain and a B chain but their cleavage sites are not definitely described yet. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. There are two alternatively spliced transcript variants encoding different isoforms described for this gene.


Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Vogel, I., et al. In Vivo 23(6):1005-1009(2009)
Dschietzig, T., et al. Regul. Pept. 155 (1-3), 163-173 (2009) :
Mookerjee, I., et al. FASEB J. 23(4):1219-1229(2009)
Svendsen, A.M., et al. Mol. Cell. Endocrinol. 296 (1-2), 10-17 (2008) :

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Cat# AP19181B
(40 western blots)
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