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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   GRPEL2 Antibody (N-term)   

GRPEL2 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - GRPEL2 Antibody (N-term) AP19185a
    GRPEL2 Antibody (N-term) (Cat. #AP19185a) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the GRPEL2 antibody detected the GRPEL2 protein (arrow).
  • WB - GRPEL2 Antibody (N-term) AP19185a
    GRPEL2 Antibody (N-term) (Cat. #AP19185a) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the GRPEL2 antibody detected the GRPEL2 protein (arrow).
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8TAA5
Other Accession NP_689620.2
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 25431 Da
Antigen Region 14-43 aa
Additional Information
Gene ID 134266
Other Names GrpE protein homolog 2, mitochondrial, Mt-GrpE#2, GRPEL2
Target/Specificity This GRPEL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human GRPEL2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGRPEL2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GRPEL2
Function Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70 (By similarity).
Cellular Location Mitochondrion matrix.
Research Areas
Citations (0)

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Background

Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70 (By similarity).

References

Lamesch, P., et al. Genomics 89(3):307-315(2007)
Naylor, D.J., et al. J. Biol. Chem. 273(33):21169-21177(1998)

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$ 295.00
$ 99.00
Cat# AP19185a
Size:
Quantity:
(40 western blots)
Availability: In Stock
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