|Application ||WB, E|
|Calculated MW||36968 Da|
|Antigen Region||229-255 aa|
|Other Names||Signal-regulatory protein beta-2, SIRP-beta-2, Protein tyrosine phosphatase non-receptor type substrate 1-like 3, Protein tyrosine phosphatase non-receptor type substrate protein, SIRPB2, PTPN1L, PTPNS1L3|
|Target/Specificity||This SIRPB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 229-255 amino acids from the C-terminal region of human SIRPB2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SIRPB2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.
Nyati, M.K., et al. Cancer Res. 66(24):11554-11559(2006)
van den Berg, T.K., et al. J. Immunol. 175(12):7788-7789(2005)
Chen, J., et al. Proc. Natl. Acad. Sci. U.S.A. 99(19):12257-12262(2002)
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