|Application ||WB, E|
|Other Accession||Q4R6Y6, NP_001034786.1|
|Calculated MW||46753 Da|
|Antigen Region||145-171 aa|
|Other Names||snRNA-activating protein complex subunit 3, SNAPc subunit 3, Proximal sequence element-binding transcription factor subunit beta, PSE-binding factor subunit beta, PTF subunit beta, Small nuclear RNA-activating complex polypeptide 3, snRNA-activating protein complex 50 kDa subunit, SNAPc 50 kDa subunit, SNAPC3, SNAP50|
|Target/Specificity||This SNAPC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-171 amino acids from the Central region of human SNAPC3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SNAPC3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.|
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Provided below are standard protocols that you may find useful for product applications.
Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.
Wu, C., et al. Proteomics 7(11):1775-1785(2007)
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Jawdekar, G.W., et al. J. Biol. Chem. 281(41):31050-31060(2006)
Humphray, S.J., et al. Nature 429(6990):369-374(2004)
Hinkley, C.S., et al. J. Biol. Chem. 278(20):18649-18657(2003)
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