|Application ||WB, E|
|Calculated MW||24036 Da|
|Antigen Region||50-77 aa|
|Other Names||Talanin, ZNF365, KIAA0844|
|Target/Specificity||This ZNF365 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-77 amino acids from the Central region of human ZNF365.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ZNF365 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in uric acid excretion.|
|Tissue Location||Isoform 4 is expressed in placenta, lung, kidney and pancreas.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes several isoforms which have different expression patterns and functions. Mutation in this gene is associated with uric acid nephrolithiasis (UAN). Alternatively spliced variants, encoding distinct proteins, have been identified.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Turnbull, C., et al. Nat. Genet. 42(6):504-507(2010)
Amre, D.K., et al. Aliment. Pharmacol. Ther. 31(11):1186-1191(2010)
Anitha, A., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (7), 967-976 (2009) :
Wang, Q., et al. Proc. Natl. Acad. Sci. U.S.A. 103(17):6512-6517(2006)
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