|Application ||WB, E|
|Other Accession||Q4KM98, Q6PCP5, Q3ZCD8, NP_064579.3|
|Predicted||Bovine, Mouse, Rat|
|Calculated MW||38465 Da|
|Antigen Region||133-162 aa|
|Other Names||Mitochondrial fission factor, MFF, C2orf33|
|Target/Specificity||This MFF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-162 amino acids from the Central region of human MFF.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MFF Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles.|
|Cellular Location||Mitochondrion outer membrane; Single-pass type IV membrane protein. Peroxisome. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle|
|Tissue Location||Highly expressed in heart, kidney, liver, brain, muscle, and stomach.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
MFF plays a role in mitochondrial and peroxisomal fission.
Gandre-Babbe, S., et al. Mol. Biol. Cell 19(6):2402-2412(2008)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
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