HOXB7 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | P09629 |
Other Accession | P18864, P09024, Q9TT89, NP_004493.3 |
Reactivity | Mouse |
Predicted | Bovine, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 24015 Da |
Antigen Region | 93-121 aa |
Gene ID | 3217 |
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Other Names | Homeobox protein Hox-B7, Homeobox protein HHOC1, Homeobox protein Hox-2C, HOXB7, HOX2C |
Target/Specificity | This HOXB7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-121 amino acids from the Central region of human HOXB7. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | HOXB7 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | HOXB7 |
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Synonyms | HOX2C |
Function | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. |
Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma. [provided by RefSeq].
References
Braig, S., et al. Cell. Mol. Life Sci. 67(20):3535-3548(2010)
Novak, E.M., et al. Eur. J. Haematol. 84(2):185-186(2010)
De Souza Setubal Destro, M.F., et al. Int. J. Oncol. 36(1):141-149(2010)
Milanovic, D., et al. Int. J. Cancer 121(6):1205-1211(2007)
Rubin, E., et al. Cancer Res. 67(4):1527-1535(2007)
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