|Application ||WB, E|
|Other Accession||Q6AYM2, Q4R5V1, Q2T9Q6, NP_055281.2|
|Predicted||Bovine, Monkey, Rat|
|Calculated MW||49672 Da|
|Antigen Region||103-132 aa|
|Other Names||Tektin-2, Tektin-t, Testicular tektin, Testicular tektin B1-like protein, TEKTB1, Tektin-B1, TEKT2|
|Target/Specificity||This TEKT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the N-terminal region of human TEKT2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TEKT2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity).|
|Cellular Location||Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme. Note=In sperm, observed in a discontinuous punctate pattern in the flagellum and in the postacrosomal head region|
|Tissue Location||Expressed at high levels in testis, trachea and fetal lung, and at lower levels in ovary, pituitary, adult lung, fetal brain and fetal kidney.|
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Provided below are standard protocols that you may find useful for product applications.
This gene product belongs to the tektin family of proteins. Tektins comprise a family of filament-forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules. This gene is expressed in the testis and its protein is localized to the flagella of the sperms, indicating that it may play a role in spermatogenesis.
Zuccarello, D., et al. Hum. Reprod. 23(4):996-1001(2008)
Tanaka, H., et al. Mol. Cell. Biol. 24(18):7958-7964(2004)
Iguchi, N., et al. Mol. Hum. Reprod. 8(6):525-530(2002)
Wolkowicz, M.J., et al. Biol. Reprod. 66(1):241-250(2002)
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