|Application ||WB, E|
|Calculated MW||56975 Da|
|Antigen Region||10-39 aa|
|Other Names||LEM domain-containing protein 2, hLEM2, LEMD2|
|Target/Specificity||This LEMD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from the N-terminal region of human LEMD2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LEMD2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in nuclear structure organization (PubMed:16339967). Required for maintaining the integrity of the nuclear envelope (PubMed:17097643).|
|Cellular Location||Nucleus inner membrane; Multi- pass membrane protein. Note=Lamina- associated protein residing in the inner nuclear membrane (INM) Localized exclusively to the nuclear envelope, giving rise to a typical rim-like staining of the nuclear periphery|
|Tissue Location||Ubiquitously expressed.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
LEMD2 is involved in nuclear structure organization.
Kestenbaum, B., et al. J. Am. Soc. Nephrol. 21(7):1223-1232(2010) Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009) : Cotsapas, C., et al. Hum. Mol. Genet. 18(18):3502-3507(2009)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.