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PMF1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q6P1K2 |
| Other Accession | NP_009152.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 23339 Da |
| Antigen Region | 109-135 aa |
| Gene ID | 100527963;11243 |
|---|---|
| Other Names | Polyamine-modulated factor 1, PMF-1, PMF1 {ECO:0000312|EMBL:AAH650311} |
| Target/Specificity | This PMF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-135 amino acids from the Central region of human PMF1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PMF1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PMF1 {ECO:0000312|EMBL:AAH65031.1} |
|---|---|
| Function | Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT. |
| Cellular Location | Nucleus. Chromosome, centromere, kinetochore Note=Associated with the kinetochore |
| Tissue Location | Highest levels of expression in heart and skeletal muscle, with significant levels expressed in kidney and liver |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT.
References
Aleman, A., et al. Clin. Cancer Res. 14(24):8236-8243(2008)
Kline, S.L., et al. J. Cell Biol. 173(1):9-17(2006)
Obuse, C., et al. Nat. Cell Biol. 6(11):1135-1141(2004)
Wang, Y., et al. Biochem. J. 366 (PT 1), 79-86 (2002) :
Wang, Y., et al. Biochem. J. 355 (PT 1), 45-49 (2001) :
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