- CITATIONS: 1
|Application ||WB, E|
|Calculated MW||52684 Da|
|Antigen Region||331-359 aa|
|Other Names||Zinc transporter 10, ZnT-10, Solute carrier family 30 member 10, SLC30A10, ZNT10, ZNT8|
|Target/Specificity||This SLC30A10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-359 amino acids from the C-terminal region of human SLC30A10.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SLC30A10 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a pivotal role in manganese transport. Manganese is an essential cation for the function of several enzymes, including some crucially important for the metabolism of neurotransmitters and other neuronal metabolic pathways.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Specifically expressed in fetal liver and fetal brain.|
Provided below are standard protocols that you may find useful for product applications.
Zinc functions as a cofactor for numerous enzymes, nuclear factors, and hormones and as an intra- and intercellular signal ion. Members of the zinc transporter (ZNT)/SLC30 subfamily of the cation diffusion facilitator family, such as SLC30A10, permit cellular efflux of zinc (Seve et al., 2004 [PubMed 15154973]).
Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3558-3566(2008)
Seve, M., et al. BMC Genomics 5 (1), 32 (2004) :
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