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SIRPB1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SIRPB1 Antibody (Center) AP19299C
    SIRPB1 Antibody (Center)(Cat. #AP19299c) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the SIRPB1 antibody detected the SIRPB1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O00241
Other Accession P78324, NP_001077379.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 43211 Da
Antigen Region 107-134 aa
Additional Information
Gene ID 10326
Other Names Signal-regulatory protein beta-1, SIRP-beta-1, CD172 antigen-like family member B, CD172b, SIRPB1
Target/Specificity This SIRPB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-134 amino acids from the Central region of human SIRPB1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSIRPB1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Detected in monocytes and dendritic cells.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].


Gaikwad, S., et al. Am. J. Pathol. 175(6):2528-2539(2009)
Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009)
Martins-de-Souza, D., et al. J Neural Transm 116(3):275-289(2009)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
van den Berg, T.K., et al. J. Immunol. 175(12):7788-7789(2005)

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$ 295.00
$ 99.00
Cat# AP19299C
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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