|Application ||WB, E|
|Calculated MW||23407 Da|
|Antigen Region||39-67 aa|
|Other Names||Recoverin, 23 kDa photoreceptor cell-specific protein, Cancer-associated retinopathy protein, Protein CAR, Rcvrn, Rcv1|
|Target/Specificity||This Mouse Rcvrn antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-67 amino acids from the N-terminal region of mouse Rcvrn.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Rcvrn Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse.|
|Tissue Location||Retina and pineal gland.|
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Provided below are standard protocols that you may find useful for product applications.
Rcvrn seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse.
Jin, K., et al. J. Neurosci. 30(36):11902-11916(2010)
Georgi, S.A., et al. J. Neurosci. 30(11):4048-4061(2010)
Sanuki, R., et al. FEBS Lett. 584(4):753-758(2010)
Brzezinski, J.A. IV, et al. Development 137(4):619-629(2010)
Chen, C.K., et al. J. Neurosci. 30(4):1213-1220(2010)
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