|Application ||WB, E|
|Other Accession||Q4KM77, O14681, Q08DE5, NP_031941.1|
|Predicted||Bovine, Human, Rat|
|Calculated MW||38933 Da|
|Antigen Region||263-290 aa|
|Other Names||Etoposide-induced protein 24, p53-induced gene 8 protein, Ei24, Pig8|
|Target/Specificity||This Mouse Ei24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-290 amino acids from the C-terminal region of mouse Ei24.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Ei24 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a negative growth regulator via p53-mediated apoptosis pathway. Regulates formation of degradative autolysosomes during autophagy (By similarity).|
|Cellular Location||Nucleus membrane; Multi-pass membrane protein. Cytoplasm Endoplasmic reticulum membrane; Multi-pass membrane protein|
|Tissue Location||Found in all the examined tissues. High expression was found in liver, skeletal muscle, pancreas, kidney heart and to a lesser extent in brain, placenta and lung|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Ei24 may play a role in the cellular response to DNA damage and/or p53-mediated apoptosis.
Bahk, Y.Y., et al. J. Proteome Res. 9(10):5270-5283(2010)
Mork, C.N., et al. FEBS Lett. 581(28):5440-5444(2007)
Lee, J., et al. Mol. Cell Proteomics 6(4):669-676(2007)
Colombo, E., et al. Mol. Cell. Biol. 25(20):8874-8886(2005)
McClive, P.J., et al. Genesis 37(2):84-90(2003)
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