CAPNS2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q96L46 |
Other Accession | Q9D7J7, NP_115706.1 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 27660 Da |
Antigen Region | 55-83 aa |
Gene ID | 84290 |
---|---|
Other Names | Calpain small subunit 2, CSS2, Calcium-dependent protease small subunit 2, CAPNS2 |
Target/Specificity | This CAPNS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the Central region of human CAPNS2. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CAPNS2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CAPNS2 |
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Function | Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. This small subunit may act as a tissue-specific chaperone of the large subunit, possibly by helping it fold into its correct conformation for activity. |
Cellular Location | Cytoplasm. Cell membrane. Note=Translocates to the plasma membrane upon calcium binding. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. This small subunit may act as a tissue-specific chaperone of the large subunit, possibly by helping it fold into its correct conformation for activity.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Ma, H., et al. Curr. Eye Res. 29 (4-5), 337-347 (2004) :
Schad, E., et al. Biochem. J. 362 (PT 2), 383-388 (2002) :
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