|Application ||WB, E|
|Calculated MW||101272 Da|
|Antigen Region||47-76 aa|
|Other Names||General transcription factor 3C polypeptide 3, Transcription factor IIIC 102 kDa subunit, TFIIIC 102 kDa subunit, TFIIIC102, Transcription factor IIIC subunit gamma, TF3C-gamma, GTF3C3|
|Target/Specificity||This GTF3C3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47-76 amino acids from the N-terminal region of human GTF3C3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GTF3C3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters.|
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Provided below are standard protocols that you may find useful for product applications.
GTF3C3 is involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters.
Dumay-Odelot, H., et al. J. Biol. Chem. 282(23):17179-17189(2007)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Zhan, Y., et al. Cell Death Differ. 9(4):439-447(2002)
Hsieh, Y.J., et al. Mol. Cell. Biol. 19(7):4944-4952(1999)
Behar, G., et al. Appl. Theor. Electrophor. 5(2):99-105(1995)
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