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CCKAR Antibody(Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CCKAR Antibody(Center) AP19386c
    CCKAR Antibody (Center)(Cat. #AP19386c) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the CCKAR antibody detected the CCKAR protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P32238
Other Accession NP_000721.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 47841 Da
Antigen Region 228-257 aa
Additional Information
Gene ID 886
Other Names Cholecystokinin receptor type A, CCK-A receptor, CCK-AR, Cholecystokinin-1 receptor, CCK1-R, CCKAR, CCKRA
Target/Specificity This CCKAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-257 amino acids from the Central region of human CCKAR.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCCKAR Antibody(Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CCKRA
Function Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Cellular Location Cell membrane; Multi-pass membrane protein.
Research Areas
Citations (0)

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This gene encodes a G-protein coupled receptor that binds non-sulfated members of the cholecystokinin (CCK) family of peptide hormones. This receptor is a major physiologic mediator of pancreatic enzyme secretion and smooth muscle contraction of the gallbladder and stomach. In the central and peripheral nervous system this receptor regulates satiety and the release of beta-endorphin and dopamine.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Cong, P., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 299 (3), G742-G750 (2010) :
Tiwari, A.K., et al. Prog. Neuropsychopharmacol. Biol. Psychiatry (2010) In press :
Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
Park, S.Y., et al. J Neurogastroenterol Motil 16(1):71-76(2010)

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$ 295.00
$ 99.00
Cat# AP19386c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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