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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   RALBP1 Antibody(N-term)   

RALBP1 Antibody(N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - RALBP1 Antibody(N-term) AP19392A
    RALBP1 Antibody (N-term)(Cat. #AP19392a) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the RALBP1 antibody detected the RALBP1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15311
Other Accession NP_006779.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 76063 Da
Antigen Region 42-71 aa
Additional Information
Gene ID 10928
Other Names RalA-binding protein 1, RalBP1, 76 kDa Ral-interacting protein, Dinitrophenyl S-glutathione ATPase, DNP-SG ATPase, Ral-interacting protein 1, RALBP1, RLIP1, RLIP76
Target/Specificity This RALBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-71 amino acids from the N-terminal region of human RALBP1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRALBP1 Antibody(N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms RLIP1, RLIP76
Function Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.
Cellular Location Membrane; Peripheral membrane protein
Tissue Location Expressed ubiquitously but at low levels. Shows a strong expression in the erythrocytes
Research Areas
Citations (0)

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RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL (see RALA; MIM 179550). Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS (MIM 601619), which in turn is activated by RAS (see HRAS; MIM 190020) (summary by Feig, 2003 [PubMed 12888294]).


Singhal, S.S., et al. Int. J. Cancer 126(6):1327-1338(2010)
Singhal, S.S., et al. Cancer Lett. 283(2):152-158(2009)
Awasthi, Y.C., et al. J Toxicol Environ Health B Crit Rev 12(7):540-551(2009)
Singhal, S.S., et al. Cancer Res. 69(10):4244-4251(2009)
Singhal, S.S., et al. Biochem. Pharmacol. 77(6):1074-1083(2009)

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$ 295.00
$ 99.00
Cat# AP19392A
(40 western blots)
Availability: In Stock
Bulk Size
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