|Application ||WB, E|
|Calculated MW||66158 Da|
|Antigen Region||29-58 aa|
|Other Names||Collagen alpha-1(X) chain, COL10A1|
|Target/Specificity||This COL10A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of human COL10A1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||COL10A1 Antibody(N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage.|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD).
Makitie, O., et al. J. Orthop. Res. 28(11):1497-1501(2010)
Wang, S., et al. Connect. Tissue Res. 51(3):188-196(2010)
Videman, T., et al. Arthritis Rheum. 60(2):470-481(2009)
Higashikawa, A., et al. Arthritis Rheum. 60(1):166-178(2009)
Zimmermann, P., et al. Arthritis Rheum. 58(9):2743-2753(2008)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.