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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ILKAP Antibody(Center)   

ILKAP Antibody(Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ILKAP Antibody(Center) AP19399c
    ILKAP Antibody (Center)(Cat. #AP19399c) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the ILKAP antibody detected the ILKAP protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H0C8
Other Accession Q9Z1Z6, Q8R0F6, Q0IIF0, NP_110395.1
Reactivity Human
Predicted Bovine, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 42907 Da
Antigen Region 93-122 aa
Additional Information
Gene ID 80895
Other Names Integrin-linked kinase-associated serine/threonine phosphatase 2C, ILKAP, ILKAP
Target/Specificity This ILKAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-122 amino acids from the Central region of human ILKAP.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsILKAP Antibody(Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation.
Cellular Location Cytoplasm.
Tissue Location Widely expressed. Highest levels expressed in striated muscle. Much lower levels evident in various smooth muscle tissues.
Research Areas
Citations (0)

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The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway.


Nakrieko, K.A., et al. Cell Cycle 7(14):2157-2166(2008)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Kumar, A.S., et al. Oncogene 23(19):3454-3461(2004)

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$ 295.00
$ 99.00
Cat# AP19399c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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