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ING2 Antibody(Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ING2 Antibody(Center) AP19411c
    ING2 Antibody (Center)(Cat. #AP19411c) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the ING2 antibody detected the ING2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H160
Other Accession NP_001555.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 32808 Da
Antigen Region 112-141 aa
Additional Information
Gene ID 3622
Other Names Inhibitor of growth protein 2, Inhibitor of growth 1-like protein, ING1Lp, p32, p33ING2, ING2, ING1L
Target/Specificity This ING2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-141 amino acids from the Central region of human ING2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsING2 Antibody(Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ING2
Synonyms ING1L
Function Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs).
Cellular Location Nucleus. Note=Predominantly nuclear. Localized to chromatin and nuclear matrix. Upon reduced PtdIns(5)P levels seems to be released from chromatin and, at least partially, translocated to the cytoplasm
Tissue Location Widely expressed. Higher expressed in colon- cancer tumor than in normal colon tissues
Citations (0)

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This gene is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis.


Ythier, D., et al. Oncogene 29(44):5946-5956(2010)
Larrieu, D., et al. EMBO Rep. 10(10):1168-1174(2009)
Kumamoto, K., et al. Int. J. Cancer 125(6):1306-1315(2009)
Borkosky, S.S., et al. J. Cancer Res. Clin. Oncol. 135(5):703-713(2009)
Unoki, M., et al. FEBS Lett. 582(28):3868-3874(2008)

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$ 295.00
$ 99.00
Cat# AP19411c
(40 western blots)
Availability: In Stock
Bulk Size
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