|Application ||WB, E|
|Calculated MW||42867 Da|
|Antigen Region||166-194 aa|
|Other Names||Dihydroorotate dehydrogenase (quinone), mitochondrial, DHOdehase, Dihydroorotate oxidase, DHODH|
|Target/Specificity||This DHODH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-194 amino acids from the Central region of human DHODH.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DHODH Antibody(Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|
|Cellular Location||Mitochondrion inner membrane; Single-pass membrane protein|
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane.
Hail, N. Jr., et al. Free Radic. Biol. Med. 49(1):109-116(2010)
Ng, S.B., et al. Nat. Genet. 42(1):30-35(2010)
Grabar, P.B., et al. Ann. Rheum. Dis. 68(8):1367-1368(2009)
Pawlik, A., et al. Pharmacogenomics 10(2):303-309(2009)
Anney, R.J., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (8), 1369-1378 (2008) :
If you have any additional inquiries please email technical services at firstname.lastname@example.org.