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Mouse Dyrk1a Antibody(C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Mouse Dyrk1a Antibody(C-term) AP19429b
    Mouse Dyrk1a Antibody (C-term)(Cat. #AP19429b) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the Mouse Dyrk1a antibody detected the Mouse Dyrk1a protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q61214
Other Accession NP_001106860.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 85494 Da
Antigen Region 718-745 aa
Additional Information
Gene ID 13548
Other Names Dual specificity tyrosine-phosphorylation-regulated kinase 1A, Dual specificity YAK1-related kinase, MP86, Protein kinase minibrain homolog, MNBH, Dyrk1a, Dyrk
Target/Specificity This Mouse Dyrk1a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 718-745 amino acids from the C-terminal region of mouse Dyrk1a.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Dyrk1a Antibody(C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Dyrk1a
Synonyms Dyrk
Function May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Modulates alternative splicing by phosphorylating the splice factor SRSF6 (By similarity). Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates such as CRY2, FOXO1, SRSF6 and SIRT1. Exhibits a sugstrate preference for proline at position P+1 and arginine at position P-3.
Cellular Location Nucleus speckle
Tissue Location Detected in brain (at protein level). Expressed in a variety of embryonic and adult tissues. Expressed abundantly in neurons of the brain, spinal cord, and retina in developing embryos.
Research Areas
Citations (0)

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Dyrk1a may play a role in a signaling pathway regulating nuclear functions of cell proliferation. Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates.


Park, J., et al. J. Biol. Chem. 285(41):31895-31906(2010)
Guo, X., et al. J. Biol. Chem. 285(17):13223-13232(2010)
Kurabayashi, N., et al. Mol. Cell. Biol. 30(7):1757-1768(2010)
Lee, Y., et al. J. Biol. Chem. 284(48):33343-33351(2009)
Noll, C., et al. PLoS ONE 4 (10), E7540 (2009) :

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$ 295.00
$ 99.00
Cat# AP19429b
(40 western blots)
Availability: In Stock
Bulk Size
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