|Application ||WB, IHC-P, FC, E|
|Calculated MW||36745 Da|
|Antigen Region||58-86 aa|
|Other Names||Lymphokine-activated killer T-cell-originated protein kinase, PDZ-binding kinase, T-LAK cell-originated protein kinase, Pbk, Topk|
|Target/Specificity||This Mouse Pbk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-86 amino acids from the N-terminal region of mouse Pbk.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Pbk Antibody(N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization (By similarity).
Zykova, T.A., et al. Clin. Cancer Res. 12(23):6884-6893(2006)
Fujibuchi, T., et al. Dev. Growth Differ. 47(9):637-644(2005)
Blackshaw, S., et al. PLoS Biol. 2 (9), E247 (2004) :
Visel, A., et al. Nucleic Acids Res. 32 (DATABASE ISSUE), D552-D556 (2004) :
Easterday, M.C., et al. Dev. Biol. 264(2):309-322(2003)
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