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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   GUCA1B Antibody(N-term)   

GUCA1B Antibody(N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GUCA1B Antibody(N-term) AP19456a
    GUCA1B Antibody (N-term) (Cat. #AP19456a) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the GUCA1B antibody detected the GUCA1B protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UMX6
Other Accession NP_002089.4
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 23420 Da
Antigen Region 29-57 aa
Additional Information
Gene ID 2979
Other Names Guanylyl cyclase-activating protein 2, GCAP 2, Guanylate cyclase activator 1B, GUCA1B, GCAP2
Target/Specificity This GUCA1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human GUCA1B.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGUCA1B Antibody(N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms GCAP2
Function Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low, and GC1 and GC2 when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of GC is a key event in recovery of the dark state of rod photoreceptors following light exposure.
Cellular Location Cell membrane. Note=Membranes of outer segment
Tissue Location Retina. Cones and rod.
Research Areas
Citations (0)

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The protein encoded by this gene is a calcium-binding protein that activates photoreceptor guanylate cyclases. This gene may have arisen due to a gene duplication event since there is a highly similar gene clustered with it on chromosome 6. Mutations in this gene can cause a form of retinitis pigmentosa. [provided by RefSeq].


Sato, M., et al. Graefes Arch. Clin. Exp. Ophthalmol. 243(3):235-242(2005)
Nishiguchi, K.M., et al. Invest. Ophthalmol. Vis. Sci. 45(11):3863-3870(2004)
Mungall, A.J., et al. Nature 425(6960):805-811(2003)
Wistow, G., et al. Mol. Vis. 8, 196-204 (2002) :
Zhang, Q.J., et al. Yi Chuan 24(1):19-21(2002)

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$ 295.00
$ 99.00
Cat# AP19456a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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