|Application ||WB, E|
|Other Accession||Q3Y4E1, NP_068799.2|
|Calculated MW||88976 Da|
|Antigen Region||106-135 aa|
|Other Names||Zinc finger protein 148, Transcription factor ZBP-89, Zinc finger DNA-binding protein 89, ZNF148, ZBP89|
|Target/Specificity||This ZNF148 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-135 amino acids from the N-terminal region of human ZNF148.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ZNF148 Antibody(N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin, stromelysin and enolase. Binds to the G-rich box in the enhancer region of these genes.|
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Provided below are standard protocols that you may find useful for product applications.
ZNF148 is involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin, stromelysin and enolase. Binds to the G-rich box in the enhancer region of these genes.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Udelhoven, M., et al. J. Endocrinol. 204(2):199-208(2010)
Chen, G.G., et al. Cancer Lett. 283(1):52-58(2009)
Feng, Y., et al. FEBS J. 276(15):4197-4206(2009)
Borghaei, R.C., et al. Biochem. Biophys. Res. Commun. 382(2):269-273(2009)
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