MYL4 Antibody(N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | P12829 |
Other Accession | NP_002467.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 21565 Da |
Antigen Region | 1-30 aa |
Gene ID | 4635 |
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Other Names | Myosin light chain 4, Myosin light chain 1, embryonic muscle/atrial isoform, Myosin light chain alkali GT-1 isoform, MYL4, MLC1 |
Target/Specificity | This MYL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MYL4. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | MYL4 Antibody(N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MYL4 |
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Synonyms | MLC1 |
Function | Regulatory light chain of myosin. Does not bind calcium. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Myosin is a hexameric ATPase cellular motor protein. It is composed of two myosin heavy chains, two nonphosphorylatable myosin alkali light chains, and two phosphorylatable myosin regulatory light chains. This gene encodes a myosin alkali light chain that is found in embryonic muscle and adult atria. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
References
Haase, H., et al. FASEB J. 20(7):865-873(2006)
Abdelaziz, A.I., et al. Adv. Exp. Med. Biol. 565, 283-292 (2005) :
Abdelaziz, A.I., et al. J. Mol. Med. 82(4):265-274(2004)
Arrell, D.K., et al. Circ. Res. 89(6):480-487(2001)
Arrell, D.K., et al. Circ. Res. 89(6):480-487(2001)
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