|Application ||WB, E|
|Other Accession||Q9Z270, Q9WV55, NP_003565.4|
|Calculated MW||27893 Da|
|Antigen Region||182-210 aa|
|Other Names||Vesicle-associated membrane protein-associated protein A, VAMP-A, VAMP-associated protein A, VAP-A, 33 kDa VAMP-associated protein, VAP-33, VAPA, VAP33|
|Target/Specificity||This VAPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 182-210 amino acids from the C-terminal region of human VAPA.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||VAPA Antibody(C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in vesicle trafficking.|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Note=Present in the plasma membrane and in intracellular vesicles, together with SNARE proteins. May also associate with the cytoskeleton. Colocalizes with OCLN at the tight junction in polarized epithelial cells|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a type IV membrane protein. It is present in the plasma membrane and intracellular vesicles. It may also be associated with the cytoskeleton. This protein may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
Furuita, K., et al. J. Biol. Chem. 285(17):12961-12970(2010)
Tuuf, J., et al. Biochem. Biophys. Res. Commun. 388(2):395-399(2009)
Saita, S., et al. J. Biol. Chem. 284(20):13766-13777(2009)
Prosser, D.C., et al. J. Cell. Sci. 121 (PT 18), 3052-3061 (2008) :
Lohoff, F.W., et al. J Neural Transm 115(9):1339-1345(2008)
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