|Application ||WB, E|
|Calculated MW||38443 Da|
|Antigen Region||110-138 aa|
|Other Names||Alpha-N-acetylgalactosaminide alpha-2, 6-sialyltransferase 5, 2499-, GD1 alpha synthase, GalNAc alpha-2, 6-sialyltransferase V, ST6GalNAc V, ST6GalNAcV, Sialyltransferase 7E, SIAT7-E, ST6GALNAC5, SIAT7E|
|Target/Specificity||This ST6GALNAC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 110-138 amino acids from the C-terminal region of human ST6GALNAC5.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ST6GALNAC5 Antibody(C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the biosynthesis of ganglioside GD1a from GM1b. It exhibits higher activity with glycolipids than with glycoproteins (By similarity).|
|Cellular Location||Golgi apparatus membrane; Single-pass type II membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
ST6GALNAC5 belongs to a family of sialyltransferases that modify proteins and ceramides on the cell surface to alter cell-cell or cell-extracellular matrix interactions (Tsuchida et al., 2003 [PubMed 12668675]).
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Harduin-Lepers, A., et al. Glycobiology 15(8):805-817(2005)
Tsuchida, A., et al. J. Biol. Chem. 278(25):22787-22794(2003)
Ikehara, Y., et al. FEBS Lett. 463 (1-2), 92-96 (1999) :
Okajima, T., et al. J. Biol. Chem. 274(43):30557-30562(1999)
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