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FUT10 Antibody(N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q6P4F1 |
| Other Accession | NP_116053.3 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 56094 Da |
| Antigen Region | 54-82 aa |
| Gene ID | 84750 |
|---|---|
| Other Names | Alpha-(1, 3)-fucosyltransferase 10, 241-, Fucosyltransferase X, Fuc-TX, FucT-X, Galactoside 3-L-fucosyltransferase 10, Fucosyltransferase 10, FUT10 |
| Target/Specificity | This FUT10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-82 amino acids from the N-terminal region of human FUT10. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FUT10 Antibody(N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FUT10 {ECO:0000303|PubMed:19088067, ECO:0000312|HGNC:HGNC:19234} |
|---|---|
| Function | Predominantly fucosylates the innermost N-acetyl glucosamine (GlcNAc) residue in biantennary N-glycan acceptors. Postulated to generate core alpha(1->3)-fucose epitope within the chitobiose unit of biantennary N-glycans, providing for a recognition signal to reorient aberrantly folded glycoproteins for degradation (PubMed:19088067). Involved in biosynthesis of Lewis X-carrying biantennary N-glycans that regulate neuron stem cell self-renewal during brain development (By similarity). |
| Cellular Location | [Isoform 1]: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein [Isoform 5]: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein |
| Tissue Location | Expressed in lung, digestive tract, gall bladder, placenta, kidney, uterus and brain. Not detected in spleen, heart, muscle, liver and pancreas. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
FUT10 is probable fucosyltransferase (By similarity).
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Mollicone, R., et al. J. Biol. Chem. 284(7):4723-4738(2009)
Baboval, T., et al. Mamm. Genome 13(9):538-541(2002)
Roos, C., et al. J. Biol. Chem. 277(5):3168-3175(2002)
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