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CSF2RA Antibody(C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CSF2RA Antibody(C-term) AP19497b
    Western blot analysis of lysate from human lung tissue lysate, using CSF2RA Antibody (C-term)(Cat. #AP19497b). AP19497b was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P15509
Other Accession NP_006131.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 46207 Da
Antigen Region 366-394 aa
Additional Information
Gene ID 1438
Other Names Granulocyte-macrophage colony-stimulating factor receptor subunit alpha, GM-CSF-R-alpha, GMCSFR-alpha, GMR-alpha, CDw116, CD116, CSF2RA, CSF2R, CSF2RY
Target/Specificity This CSF2RA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-394 amino acids from the C-terminal region of human CSF2RA.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCSF2RA Antibody(C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CSF2RA
Synonyms CSF2R, CSF2RY
Function Low affinity receptor for granulocyte-macrophage colony- stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.
Cellular Location Cell membrane; Single-pass type I membrane protein [Isoform 4]: Secreted.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble.

References

Mirza, S., et al. Biochem. J. 426(3):307-317(2010)
Sun, S., et al. Brain Res. 1268, 13-16 (2009) :
Suzuki, T., et al. J. Exp. Med. 205(12):2703-2710(2008)
Martinez-Moczygemba, M., et al. J. Exp. Med. 205(12):2711-2716(2008)
Hansen, G., et al. Cell 134(3):496-507(2008)

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$ 182.50
$ 70.00
Cat# AP19497b
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