|Application ||WB, IHC-P, E|
|Other Accession||Q8BGD9, Q8WYK5|
|Calculated MW||69151 Da|
|Antigen Region||546-575 aa|
|Other Names||Eukaryotic translation initiation factor 4B, eIF-4B, EIF4B|
|Target/Specificity||This EIF4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 546-575 amino acids from the C-terminal region of human EIF4B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||EIF4B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'- terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
EIF4B is required for the binding of mRNA to ribosomes. It functions in close association with EIF4-F and EIF4-A by binding near the 5'- terminal cap of mRNA in presence of EIF-4F and ATP. This gene also promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F
Doepker, R.C., et al., J. Virol. 78(9):4684-4699 (2004).
Fleming, K., et al., Biochemistry 42(30):8966-8975 (2003).
Milburn, S.C., et al., EMBO J. 9(9):2783-2790 (1990).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.