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TMX3 Antibody(C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q96JJ7 |
| Other Accession | NP_061895.3 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 51872 Da |
| Antigen Region | 402-431 aa |
| Gene ID | 54495 |
|---|---|
| Other Names | Protein disulfide-isomerase TMX3, Thioredoxin domain-containing protein 10, Thioredoxin-related transmembrane protein 3, TMX3, KIAA1830, TXNDC10 |
| Target/Specificity | This TMX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 402-431 amino acids from the C-terminal region of human TMX3. |
| Dilution | WB~~1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TMX3 Antibody(C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TMX3 |
|---|---|
| Synonyms | KIAA1830, TXNDC10 |
| Function | Probable disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. May act as a dithiol oxidase (PubMed:15623505). Acts as a regulator of endoplasmic reticulum-mitochondria contact sites via its ability to regulate redox signals (PubMed:31304984). |
| Cellular Location | Endoplasmic reticulum membrane; Single-pass membrane protein |
| Tissue Location | Widely expressed. Expressed in brain, testis, lung, skin, kidney, uterus, bone, stomach, liver, prostate, placenta, eye and muscle. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Probable disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. May act as a dithiol oxidase.
References
Chao, R., et al. PLoS ONE 5 (5), E10565 (2010) :
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Haugstetter, J., et al. J. Biol. Chem. 282(46):33859-33867(2007)
Haugstetter, J., et al. J. Biol. Chem. 280(9):8371-8380(2005)
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