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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   DPEP1 Antibody(N-term)   

DPEP1 Antibody(N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DPEP1 Antibody(N-term) AP19662a
    DPEP1 Antibody (N-term) (Cat. #AP19662a) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the DPEP1 antibody detected the DPEP1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P16444
Other Accession NP_001121613.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 45674 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 1800
Other Names Dipeptidase 1, Dehydropeptidase-I, Microsomal dipeptidase, Renal dipeptidase, hRDP, DPEP1, MDP, RDP
Target/Specificity This DPEP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DPEP1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDPEP1 Antibody(N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DPEP1
Synonyms MDP, RDP
Function Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity.
Cellular Location Apical cell membrane; Lipid-anchor, GPI- anchor. Cell projection, microvillus membrane; Lipid-anchor, GPI- anchor. Note=Brush border membrane
Research Areas
Citations (0)

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DPEP1 (EC is a kidney membrane enzyme that hydrolyzes a variety of dipeptides and is implicated in renal metabolism of glutathione and its conjugates, e.g., leukotriene D4 (Kozak and Tate, 1982 [PubMed 6122685]). DPEP1 is responsible for hydrolysis of the beta-lactam ring of antibiotics, such as penem and carbapenem (Campbell et al., 1984 [PubMed 6334084]). Earlier, beta-lactamase enzymes were thought to occur only in bacteria, where their probable function was in protecting the organisms against the action of beta-lactam antibiotics. These antibiotics exhibit selective toxicity against bacteria but virtual inertness against many eukaryotic cells (Adachi et al., 1990 [PubMed 2303490]).


Nan, H., et al. J. Invest. Dermatol. 129(9):2250-2257(2009)
Pare, G., et al. Circ Cardiovasc Genet 2(2):142-150(2009)
Nitanai, Y., et al. J. Mol. Biol. 321(2):177-184(2002)
Kera, Y., et al. Comp. Biochem. Physiol. B, Biochem. Mol. Biol. 123(1):53-58(1999)
Satoh, S., et al. Biotechnol. Prog. 10(2):134-140(1994)

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$ 295.00
$ 99.00
Cat# AP19662a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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