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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Mouse Krt6a Antibody(Center)   

Mouse Krt6a Antibody(Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Mouse Krt6a Antibody(Center) AP19689c
    Mouse Krt6a Antibody (Center) (Cat. #AP19689c) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the Mouse Krt6a antibody detected the Mouse Krt6a protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P50446
Other Accession Q9Z331, NP_032502.3
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 59335 Da
Antigen Region 212-240 aa
Additional Information
Gene ID 16687
Other Names Keratin, type II cytoskeletal 6A, Cytokeratin-6A, CK-6A, Keratin-6-alpha, mK6-alpha, Keratin-6A, K6A, Krt6a, Ker2, Krt2-6, Krt2-6a, Krt6
Target/Specificity This Mouse Krt6a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-240 amino acids from the Central region of mouse Krt6a.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Krt6a Antibody(Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Krt6a
Synonyms Ker2, Krt2-6, Krt2-6a, Krt6
Function Epidermis-specific type I keratin involved in wound healing (PubMed:10866680). Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration (PubMed:10866680). Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair (PubMed:22529101).
Tissue Location Predominates in the adult trunk skin, tongue, trachea/esophagus and eye. In adult skin, localization is restricted to hair follicles, where it is localized predominantly in the outer root sheath.
Research Areas
Citations (0)

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Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation related keratins). Keratin 6 is found in hair follicles, neck squamous cell carcinomas, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation. There are at least six isoforms of human type II keratin 6 (K6), K6A being the most abundant representing about 77% of all forms found in epithelia.


Sehic, A., et al. Eur. J. Oral Sci. 117(2):93-104(2009)
Chen, J., et al. J. Invest. Dermatol. 128(2):270-279(2008)
Cui, C.Y., et al. Hum. Mol. Genet. 16(21):2583-2590(2007)
Gu, L.H., et al. J. Invest. Dermatol. 127(5):1061-1073(2007)
Kurek, D., et al. Development 134(2):261-272(2007)

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$ 295.00
$ 99.00
Cat# AP19689c
(40 western blots)
Availability: In Stock
Bulk Size
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