|Application ||WB, E|
|Other Accession||Q80Z10, NP_001171664.1, NP_054729.3, NP_937829.3, NP_937831.1|
|Calculated MW||148243 Da|
|Antigen Region||220-248 aa|
|Other Names||Astrotactin-2, ASTN2, KIAA0634|
|Target/Specificity||This ASTN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-248 amino acids from the N-terminal region of human ASTN2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ASTN2 Antibody(N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein that is expressed in the brain and may function in neuronal migration, based on functional studies of the related astrotactin 1 gene in human and mouse. A deletion at this locus has been associated with schizophrenia. Multiple transcript variants encoding different proteins have been found for this locus.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Adkins, D.E., et al. Mol. Psychiatry (2010) In press :
Lesch, K.P., et al. J Neural Transm 115(11):1573-1585(2008)
Vrijenhoek, T., et al. Am. J. Hum. Genet. 83(4):504-510(2008)
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