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CLSTN2 Antibody(Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9H4D0 |
| Other Accession | NP_071414.2 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 107006 Da |
| Antigen Region | 743-770 aa |
| Gene ID | 64084 |
|---|---|
| Other Names | Calsyntenin-2, Alcadein-gamma, Alc-gamma, CLSTN2, CS2 |
| Target/Specificity | This CLSTN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 743-770 amino acids from the Central region of human CLSTN2. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CLSTN2 Antibody(Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CLSTN2 (HGNC:17448) |
|---|---|
| Synonyms | CS2 |
| Function | Postsynaptic adhesion molecule that binds to presynaptic neurexins to mediate synapse formation, and which is involved in learning and memory (By similarity). Promotes synapse development by acting as a cell adhesion molecule at the postsynaptic membrane, which associates with neurexin-alpha at the presynaptic membrane (By similarity). |
| Cellular Location | Postsynaptic cell membrane {ECO:0000250|UniProtKB:Q9ER65}; Single-pass type I membrane protein. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9ER65}; Single-pass type I membrane protein. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9ER65}; Single-pass type I membrane protein. Cell projection, dendrite {ECO:0000250|UniProtKB:Q9ER65}. Note=Most prominent in the postsynaptic specializations of asymmetric (type I) synapses with both axodendritic and axospinous localization {ECO:0000250|UniProtKB:Q9ER65} |
| Tissue Location | Restricted to the brain. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
CLSTN2 may modulate calcium-mediated postsynaptic signals (By similarity).
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Preuschhof, C., et al. Neuropsychologia 48(2):402-408(2010)
Zhang, H., et al. Neuropsychopharmacology 34(12):2508-2516(2009)
Henckaerts, L., et al. Clin. Gastroenterol. Hepatol. 7(9):972-980(2009)
Jacobsen, L.K., et al. Biol. Psychiatry 65(8):671-679(2009)
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