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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   NXT1 Antibody (C-term)   

NXT1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - NXT1 Antibody (C-term) AP19752b
    NXT1 Antibody (C-term) (Cat. #AP19752b) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the NXT1 antibody detected the NXT1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UKK6
Other Accession Q9QZV9, Q2KIW0, NP_037380.1
Reactivity Mouse
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 15847 Da
Antigen Region 85-111 aa
Additional Information
Gene ID 29107
Other Names NTF2-related export protein 1, Protein p15, NXT1
Target/Specificity This NXT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-111 amino acids from the C-terminal region of human NXT1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNXT1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NXT1
Function Stimulator of protein export for NES-containing proteins. Also plays a role in the nuclear export of U1 snRNA, tRNA, and mRNA. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5.
Cellular Location Nucleus. Nucleus speckle. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm
Research Areas
Citations (0)

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The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene.


Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
Forler, D., et al. Nat. Biotechnol. 21(1):89-92(2003)
Katahira, J., et al. J. Biol. Chem. 277(11):9242-9246(2002)
Wiegand, H.L., et al. Mol. Cell. Biol. 22(1):245-256(2002)
Deloukas, P., et al. Nature 414(6866):865-871(2001)

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$ 295.00
$ 99.00
Cat# AP19752b
(40 western blots)
Availability: In Stock
Bulk Size
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