|Application ||WB, E|
|Other Accession||P17431, P23950, NP_004917.2|
|Calculated MW||36314 Da|
|Antigen Region||64-93 aa|
|Other Names||Zinc finger protein 36, C3H1 type-like 1, Butyrate response factor 1, EGF-response factor 1, ERF-1, Protein TIS11B, ZFP36L1, BERG36, BRF1, ERF1, RNF162B, TIS11B|
|Target/Specificity||This ZFP36L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-93 amino acids from the N-terminal region of human ZFP36L1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ZFP36L1 Antibody(N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||BERG36, BRF1, ERF1, RNF162B, TIS11B|
|Function||Probable regulatory protein involved in regulating the response to growth factors.|
|Cellular Location||Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm.|
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Provided below are standard protocols that you may find useful for product applications.
This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors.
Hacker, C., et al. Growth Factors 28(3):178-190(2010)
Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010)
Sinha, S., et al. J. Biol. Chem. 284(47):32610-32618(2009)
Cheng, Z., et al. Genes Dev. 23(9):1106-1118(2009)
Baou, M., et al. Leukemia 23(5):986-989(2009)
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