|Application ||WB, E|
|Calculated MW||91955 Da|
|Antigen Region||288-317 aa|
|Other Names||Polyserase-2, 3421-, Polyserine protease 2, Serine protease 36, PRSS36|
|Target/Specificity||This PRSS36 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 288-317 amino acids from the Central region of human PRSS36.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PRSS36 Antibody(Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Serine protease. Hydrolyzes the peptides N-t-Boc-Gln- Ala-Arg-AMC and N-t-Boc-Gln-Gly-Arg-AMC and, to a lesser extent, N-t-Boc-Ala-Phe-Lys-AMC and N-t-Boc-Val-Leu-Lys-AMC. Has a preference for substrates with an Arg instead of a Lys residue in position P1.|
|Cellular Location||Secreted, extracellular space, extracellular matrix. Note=Not attached to membranes|
|Tissue Location||Expressed in fetal kidney, skeletal muscle, liver, placenta and heart. Also expressed in tumor cell lines derived from lung and colon adenocarcinomas|
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Provided below are standard protocols that you may find useful for product applications.
Serine protease. Hydrolyzes the peptides N-t-Boc-Gln-Ala-Arg-AMC and N-t-Boc-Gln-Gly-Arg-AMC and, to a lesser extent, N-t-Boc-Ala-Phe-Lys-AMC and N-t-Boc-Val-Leu-Lys-AMC. Has a preference for substrates with an Arg instead of a Lys residue in position P1.
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
Cal, S., et al. J. Biol. Chem. 280(3):1953-1961(2005)
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