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JUN Antibody(Y170)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP1984f | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
JUN Antibody(Y170) - Product info | |
| Application | WB
|
| Primary Accession | P05412 |
| Other Accession | P17325, P56432, P05627, P18870, O77627 |
| Reactivity | Human |
| Predicted | Bovine, Chicken, Mouse, Pig, Rat |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 35676 Da |
JUN Antibody(Y170) - Additional info | |
| Gene ID 3725 | |
| Other Names JUN; Transcription factor AP-1; Activator protein 1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39 | |
| Target/Specificity This JUN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding Y170 of human JUN. | |
| Dilution WB~~1:50~100WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions JUN Antibody(Y170) is for research use only and not for use in diagnostic or therapeutic procedures. | |
JUN Antibody(Y170) - Protein Information | |
| Name JUN | |
| Function Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation | |
| Cellular Location Nucleus. | |
JUN Antibody(Y170) - Related products
AP1984b: JUN Antibody (C-term R272)
AP1984i: JUN Antibody (C-term)
AP1984k: JUN Antibody (C-term E248)
AP2507b: AP-1 Sumoylation Site Antibody
AP3072a: Phospho-cJun-S63 Antibody
AP3073a: Phospho-cJun-S63 Antibody
AP3075a: Phospho-cJun-S73 Antibody
AP3292a: Phospho-JUN-T239 Antibody
AP3293a: Phospho-JUN-Y170 Antibody
AP3294a: Phospho-JUN-T243 Antibody
AP3295a: Phospho-JUN-T249 Antibody
AP3380a: Phospho-JUN-S63 Antibody
AP3402a: Phospho-JUN-S73 Antibody
BP1984b: JUN Antibody (C-term R272) Blocking Peptide
BP1984c: JUN Antibody (T239) Blocking Peptide
BP1984d: JUN Antibody (S63) Blocking Peptide
BP1984e: JUN Antibody (S73) Blocking Peptide
BP1984f: JUN Antibody(Y170) Blocking Peptide
BP1984g: JUN Antibody (T243) Blocking Peptide
BP1984h: JUN Antibody (T249) Blocking Peptide
BP1984k: JUN Antibody (C-term E248) Blocking peptide
BP2507b: AP-1 Sumoylation site Antibody Blocking Peptide
BP3072a: Phospho-cJun-S63 Antibody Blocking Peptide
BP3073a: Phospho-cJun-S63 Antibody Blocking Peptide
BP3075a: Phospho-cJun-S73 Antibody Blocking Peptide
BP3292a: Phospho-JUN-T239 Antibody Blocking Peptide
BP3293a: Phospho-JUN-Y170 Antibody Blocking Peptide
BP3294a: Phospho-JUN-T243 Antibody Blocking Peptide
BP3295a: Phospho-JUN-T249 Antibody Blocking Peptide
BP3380a: Phospho-JUN-S63 Antibody Blocking Peptide
BP3402a: Phospho-JUN-S73 Antibody Blocking Peptide
AJ1188a: c-Jun Antibody (C-term)
AJ1188b: c-Jun Antibody (N-term)
AJ1188c: c-Jun Antibody Phospho (pS63)
JUN Antibody(Y170) - Application data
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Western blot analysis of JUN (arrow) using rabbit polyclonal JUN Antibody (Y170) (Cat.#AP1984f). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the JUN gene (Lane 2) (Origene Technologies).
JUN Antibody(Y170) - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
JUN interacts directly with specific target DNA sequences to regulate gene expression. Jun recognizes the AP-1 consensus sequence TGACTCA, a response element that confers sensitivity to one of the tumor-promoting Phorbol esters, 12-O-tetradecanoyl-phorbol-13-acetate (see also: TRE, TPA response element). Jun itself forms homodimers or heterodimers with junD and junB and also interacts with the oncogene product fos, forming jun-fos heterodimers.
REFERENCES
Fujita,S., J. Mol. Biol. 378 (3), 492-504 (2008) Gan,X.Q., . Cell Biol. 180 (6), 1087-1100 (2008) Yogev,O., Cancer Res. 68 (5), 1398-1406 (2008)
