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JUN Antibody (C-term E248)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP1984k | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP1984k-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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- Citiations : 0
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JUN Antibody (C-term E248) - Product info | |
| Application | WB, IHC, FC
|
| Primary Accession | P05412 |
| Other Accession | P17325, P56432, P05627, P18870, O77627, NP_002219 |
| Reactivity | Human, Mouse |
| Predicted | Bovine, Chicken, Pig, Rat |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 35676 Da |
JUN Antibody (C-term E248) - Additional info | |
| Gene ID 3725 | |
| Other Names JUN; Transcription factor AP-1; Activator protein 1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39 | |
| Target/Specificity This JUN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 240-269 amino acids from the C-terminal region of human JUN. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:50~100 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions JUN Antibody (C-term E248) is for research use only and not for use in diagnostic or therapeutic procedures. | |
JUN Antibody (C-term E248) - Protein Information | |
| Name JUN | |
| Function Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation | |
| Cellular Location Nucleus. | |
JUN Antibody (C-term E248) - Related products
AP1984b: JUN Antibody (C-term R272)
AP1984i: JUN Antibody (C-term)
AP1984k: JUN Antibody (C-term E248)
AP2507b: AP-1 Sumoylation Site Antibody
AP3072a: Phospho-cJun-S63 Antibody
AP3073a: Phospho-cJun-S63 Antibody
AP3075a: Phospho-cJun-S73 Antibody
AP3292a: Phospho-JUN-T239 Antibody
AP3293a: Phospho-JUN-Y170 Antibody
AP3294a: Phospho-JUN-T243 Antibody
AP3295a: Phospho-JUN-T249 Antibody
AP3380a: Phospho-JUN-S63 Antibody
AP3402a: Phospho-JUN-S73 Antibody
BP1984b: JUN Antibody (C-term R272) Blocking Peptide
BP1984c: JUN Antibody (T239) Blocking Peptide
BP1984d: JUN Antibody (S63) Blocking Peptide
BP1984e: JUN Antibody (S73) Blocking Peptide
BP1984f: JUN Antibody(Y170) Blocking Peptide
BP1984g: JUN Antibody (T243) Blocking Peptide
BP1984h: JUN Antibody (T249) Blocking Peptide
BP1984k: JUN Antibody (C-term E248) Blocking peptide
BP2507b: AP-1 Sumoylation site Antibody Blocking Peptide
BP3072a: Phospho-cJun-S63 Antibody Blocking Peptide
BP3073a: Phospho-cJun-S63 Antibody Blocking Peptide
BP3075a: Phospho-cJun-S73 Antibody Blocking Peptide
BP3292a: Phospho-JUN-T239 Antibody Blocking Peptide
BP3293a: Phospho-JUN-Y170 Antibody Blocking Peptide
BP3294a: Phospho-JUN-T243 Antibody Blocking Peptide
BP3295a: Phospho-JUN-T249 Antibody Blocking Peptide
BP3380a: Phospho-JUN-S63 Antibody Blocking Peptide
BP3402a: Phospho-JUN-S73 Antibody Blocking Peptide
AJ1188a: c-Jun Antibody (C-term)
AJ1188b: c-Jun Antibody (N-term)
AJ1188c: c-Jun Antibody Phospho (pS63)
JUN Antibody (C-term E248) - Application data
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JUN Antibody (C-term E248) (Cat. #AP1984k) western blot analysis in mouse lung tissue lysates (15ug/lane).This demonstrates the JUN antibody detected JUN protein (arrow).
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JUN Antibody (C-term E248) (Cat. #AP1984k) immunohistochemistry analysis in formalin fixed and paraffin embedded human Lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the JUN Antibody (C-term E248) for immunohistochemistry. Clinical relevance has not been evaluated.
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JUN Antibody (C-term E248) (Cat. #AP1984k) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
JUN Antibody (C-term E248) - Research Areas
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BACKGROUND
JUN is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.
REFERENCES
Lin, A., et al. Cell 70(5):777-789(1992) Lin, A., et al. Cell 70(5):777-789(1992) Chevray, P.M., et al. Proc. Natl. Acad. Sci. U.S.A. 89(13):5789-5793(1992) Bengal, E., et al. Cell 68(3):507-519(1992) Alvarez, E., et al. J. Biol. Chem. 266(23):15277-15285(1991)
