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LRRC19 Antibody(C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9H756 |
| Other Accession | NP_075052.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 42334 Da |
| Antigen Region | 289-318 aa |
| Gene ID | 64922 |
|---|---|
| Other Names | Leucine-rich repeat-containing protein 19, LRRC19 |
| Target/Specificity | This LRRC19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 289-318 amino acids from the C-terminal region of human LRRC19. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | LRRC19 Antibody(C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LRRC19 (HGNC:23379) |
|---|---|
| Function | Pathogen-recognition receptor which mediates the activation of TRAF2- and TRAF6 NF-kappa-B signaling pathways and induces the expression of pro-inflammatory cytokines (PubMed:19679103, PubMed:25026888). In kidney, prevents infection by uropathogenic bacteria by inducing the production of cytokines, chemokines and antimicrobial substances. In gut, involved in host-microbiota interactions, plays a critical role in promoting the recruitment of immune cells and intestinal inflammation (By similarity). |
| Cellular Location | Membrane; Single-pass type I membrane protein |
| Tissue Location | Expressed in renal collecting duct epithelial cells. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein is unknown.
References
Chai, L., et al. Biochem. Biophys. Res. Commun. 388(3):543-548(2009)
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$ 182.50
$ 70.00
Cat# AP19872b
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