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UGT2B28 Antibody(Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - UGT2B28 Antibody(Center) AP19881c
    UGT2B28 Antibody (Center) (Cat. #AP19881c) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the UGT2B28 antibody detected the UGT2B28 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9BY64
Other Accession Q8WN97, O77649, O97951, O75795, P54855, O75310, P36537, O02663, P16662, P06133, NP_444267.1
Reactivity Human
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 60906 Da
Antigen Region 218-246 aa
Additional Information
Gene ID 54490
Other Names UDP-glucuronosyltransferase 2B28, UDPGT 2B28, UGT2B28
Target/Specificity This UGT2B28 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-246 amino acids from the Central region of human UGT2B28.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsUGT2B28 Antibody(Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name UGT2B28
Function UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme has glucuronidating capacity with steroid substrates such as 5-beta-androstane 3-alpha,17-beta- diol, estradiol, ADT, eugenol and bile acids. Only isoform 1 seems to be active.
Cellular Location Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein
Tissue Location Expressed in the liver, breast and kidney.
Research Areas
Citations (0)

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Background

UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme has glucuronidating capacity with steroid substrates such as 5-beta-androstane 3-alpha,17-beta-diol, estradiol, ADT, eugenol and bile acids. Only isoform 1 seems to be active.

References

Setlur, S.R., et al. Cancer Epidemiol. Biomarkers Prev. 19(1):229-239(2010)
Ross, C.J., et al. Nat. Genet. 41(12):1345-1349(2009)
Menard, V., et al. Hum. Mutat. 30(9):1310-1319(2009)
Levesque, E., et al. Biochemistry 40(13):3869-3881(2001)

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$ 295.00
$ 99.00
Cat# AP19881c
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
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