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NR2E1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - NR2E1 Antibody (Center) AP19904c
    NR2E1 Antibody (Center) (Cat. #AP19904c) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the NR2E1 antibody detected the NR2E1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y466
Other Accession P70052, Q64104, Q91379, NP_003260.1
Reactivity Human
Predicted Chicken, Mouse, Xenopus
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 42589 Da
Antigen Region 75-102 aa
Additional Information
Gene ID 7101
Other Names Nuclear receptor subfamily 2 group E member 1, Nuclear receptor TLX, Protein tailless homolog, Tll, hTll, NR2E1, TLX
Target/Specificity This NR2E1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-102 amino acids from the Central region of human NR2E1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNR2E1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NR2E1
Synonyms TLX
Function Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half- site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity (By similarity). May be required to pattern anterior brain differentiation. Involved in the regulation of retinal development and essential for vision. During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity (By similarity). May be involved in retinoic acic receptor (RAR) regulation in retinal cells.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407}
Tissue Location Brain specific. Present in all brain sections tested, highest levels in the caudate nucleus and hippocampus, weakest levels in the thalamus.
Research Areas
Citations (0)

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Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. May be required for brain development. May be involved in the regulation of retinal development (By similarity).


Liu, H.K., et al. Genes Dev. 24(7):683-695(2010)
Iwahara, N., et al. Biochem. Biophys. Res. Commun. 386(4):671-675(2009)
de Krom, M., et al. Biol. Psychiatry 65(7):625-630(2009)
Kumar, R.A., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (6), 880-889 (2008) :
Yokoyama, A., et al. Mol. Cell. Biol. 28(12):3995-4003(2008)

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$ 295.00
$ 99.00
Cat# AP19904c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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