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HIST2H2AC Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - HIST2H2AC Antibody (Center) AP19918c
    HIST2H2AC Antibody (Center) (Cat. #AP19918c) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the HIST2H2AC antibody detected the HIST2H2AC protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16777
Other Accession P84051, Q7ZUY3, A9UMV8, Q8R1M2, Q4R3X5, Q9BTM1, P70082, Q3ZBX9, P02263, P35062, P06898, Q64523, A1A4R1, Q64522, Q8IUE6, P0CC09, Q6GSS7, Q6FI13, P06897, P02262, P0C0S8, P0C0S9, Q99878, Q96KK5, P0C170, P0C169, Q93077, NP_003508.1
Reactivity Human
Predicted Rat, Bovine, Xenopus, Mouse, Chicken, Monkey, Zebrafish, Drosophila
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 13988 Da
Antigen Region 18-46 aa
Additional Information
Gene ID 8338
Other Names Histone H2A type 2-C, Histone H2A-GL101, Histone H2A/q, HIST2H2AC, H2AFQ
Target/Specificity This HIST2H2AC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the Central region of human HIST2H2AC.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHIST2H2AC Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms H2AFQ
Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Cellular Location Nucleus. Chromosome.
Citations (0)

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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family.


Ishibashi, T., et al. Biochemistry 48(22):5007-5017(2009)
Karaczyn, A.A., et al. Ann. Clin. Lab. Sci. 39(3):251-262(2009)
Pinato, S., et al. BMC Mol. Biol. 10, 55 (2009) :
Guerrero-Santoro, J., et al. Cancer Res. 68(13):5014-5022(2008)
Zhao, Y., et al. Mol. Cell 29(1):92-101(2008)

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$ 295.00
$ 99.00
Cat# AP19918c
(40 western blots)
Availability: In Stock
Bulk Size
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