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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   RAB7B Antibody (C-term)   

RAB7B Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - RAB7B Antibody (C-term) AP19936B
    RAB7B Antibody (C-term) (Cat. #AP19936b) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the RAB7B antibody detected the RAB7B protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96AH8
Other Accession NP_796377.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 22511 Da
Antigen Region 168-197 aa
Additional Information
Gene ID 338382
Other Names Ras-related protein Rab-7b, RAB7B
Target/Specificity This RAB7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-197 amino acids from the C-terminal region of human RAB7B.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRAB7B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAB7B
Function Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway.
Cellular Location Late endosome. Lysosome. Golgi apparatus, trans-Golgi network. Golgi apparatus. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side Note=Recruited to phagosomes containing S.aureus or M.tuberculosis
Tissue Location Expressed in heart, placenta, lung, skeletal muscle and peripheral blood leukocyte
Research Areas
Citations (0)

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Protein transport. Probably involved in vesicular traffic (By similarity).


Progida, C., et al. J. Cell. Sci. 123 (PT 9), 1480-1491 (2010) :
Yang, M., et al. Biochem. Biophys. Res. Commun. 318(3):792-799(2004)

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$ 295.00
$ 99.00
Cat# AP19936B
(40 western blots)
Availability: In Stock
Bulk Size
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