ADPRH Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | P54922 |
Other Accession | Q32KR8, NP_001116.1 |
Reactivity | Human |
Predicted | Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 39507 Da |
Antigen Region | 306-334 aa |
Gene ID | 141 |
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Other Names | [Protein ADP-ribosylarginine] hydrolase, ADP-ribosylarginine hydrolase, ADP-ribose-L-arginine cleaving enzyme, ADPRH, ARH1 |
Target/Specificity | This ADPRH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-334 amino acids from the C-terminal region of human ADPRH. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ADPRH Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ADPRH |
---|---|
Synonyms | ARH1 |
Function | Specifically acts as an arginine mono-ADP-ribosylhydrolase by mediating the removal of mono-ADP-ribose attached to arginine residues on proteins. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The enzyme encoded by this gene catalyzes removal of mono-ADP-ribose from arginine residues of proteins in the ADP-ribosylation cycle. Unlike the rat and mouse enzymes, which require DTT for maximal activity, the human enzyme is DTT-independent.
References
Kernstock, S., et al. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 65 (PT 5), 529-532 (2009) :
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Weber, F., et al. J. Clin. Endocrinol. Metab. 90(2):1149-1155(2005)
Glowacki, G., et al. Protein Sci. 11(7):1657-1670(2002)
Zolkiewska, A., et al. Adv. Exp. Med. Biol. 419, 297-303 (1997) :
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