|Application ||WB, E|
|Calculated MW||36599 Da|
|Antigen Region||75-101 aa|
|Other Names||Tartrate-resistant acid phosphatase type 5, TR-AP, Tartrate-resistant acid ATPase, TrATPase, Type 5 acid phosphatase, ACP5|
|Target/Specificity||This ACP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-101 amino acids from the N-terminal region of human ACP5.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ACP5 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in osteopontin/bone sialoprotein dephosphorylation. Its expression seems to increase in certain pathological states such as Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. [provided by RefSeq].
Shih, K.C., et al. Metab. Clin. Exp. 59(1):144-151(2010)
Wu, Y.Y., et al. BMC Cancer 10, 158 (2010) :
Baranzini, S.E., et al. Hum. Mol. Genet. 18(4):767-778(2009)
Qin, Y.J., et al. Acta Pharmacol. Sin. 29(12):1493-1498(2008)
de Souza Malaspina, T.S., et al. J. Mol. Histol. 39(6):627-634(2008)
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